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- PFC Lowers Antibodies!
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- December (11)
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PFC Exposure Associated with Reduced Response to Childhood Vaccines
Exposure to perfluorinated compounds (PFCs) is associated with reduced antibody responses to childhood immunizations, according to a JAMA study. (PFCs are widely used in manufacturing and food packaging and can contaminate food and water.)
The study included some 600 children living on the Faroe Islands. Researchers measured maternal serum concentrations of PFCs during pregnancy, as well as concentrations in the children at age 5 years, before their tetanus and diphtheria booster. Antibody responses to tetanus and diphtheria were measured before the booster and 2 years afterward.
Increased maternal PFC concentrations were associated with reduced antibody levels in the children at age 5. Similarly, increased serum PFCs at age 5 were linked to reduced antibody responses at age 7.
The authors conclude: "These results indicate that PFC exposures at commonly prevalent serum concentrations are associated with lower antibody responses ... and an increased risk of antibody concentrations below the level needed to provide long-term protection." They add that the findings "may reflect a more general immune system deficit."
JAMA article (Free abstract)
Comment: What I take from this study is that we can't measure the effects chemicals in our lives (whether taken in medication form, consumed in our food, or inhaled in the air we breathe) have on our health. In this case, the effect on our immune system. The more you can do to reduce chemicals in your life, the healthier you will be. You can't eliminate all chemicals because there are things you can't control, but certainly the less the better! See my previous blog